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Paper 2

Inheritance, Variation, and Evolution

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Practice this
DNA double helix labelled diagram

Remember: genes are sections of DNA that code for proteins.

Key Facts

  • Genotype is the genetic makeup; phenotype is the expressed characteristic.
  • A dominant allele is expressed even with one copy.
  • Homozygous means two identical alleles; heterozygous means two different alleles.
  • Sex is determined by XX and XY chromosomes.

Topics Covered

DNA and Genes

What you need to know

  • DNA is made of two strands coiled in a double helix.
  • Genes are sections of DNA that code for proteins.

Exam Tips

  • Use the word "allele" for versions of a gene.

Inheritance and Punnett Squares

What you need to know

  • Use Punnett squares to predict ratios.
  • Dominant alleles are shown with capital letters.

Exam Tips

  • State the genotype and phenotype ratios separately.

Natural Selection

What you need to know

  • Variation within a species can give survival advantages.
  • Those with advantageous traits reproduce and pass on alleles.

Exam Tips

  • State variation, selection, reproduction in that order.

Selective Breeding

What you need to know

  • Select parents with desired traits and breed repeatedly.
  • May reduce genetic diversity and increase inherited problems.

Exam Tips

  • Give one benefit and one risk to secure full marks.

Key Terms

Allele

Different versions of the same gene.

Phenotype

Observable characteristics caused by genes and environment.

Genotype

The alleles an organism has.

Homozygous

Two identical alleles for a gene.

Heterozygous

Two different alleles for a gene.

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Common Exam Questions

Explain how antibiotic resistance develops in bacteria.

5 markshardPaper 2

Model Answer

Random mutations create resistant bacteria. Antibiotics kill non-resistant bacteria, leaving resistant ones to survive, reproduce, and pass on resistance.

What examiners want to see

  • Mention mutation and selection.
  • Link to survival and reproduction.

A heterozygous brown eye parent (Bb) and blue eye parent (bb) have children. Give the ratio of brown to blue.

2 marksmediumPaper 2

Model Answer

1:1

What examiners want to see

  • Use a Punnett square.
  • State the ratio clearly.

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